Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options
نویسندگان
چکیده
A pharmaco-economic study of the administration of adjunctive therapy in patients with chronic epilepsy is described. A decision-analytic model has been used, which represents the consequences of treatment over a 1-year time period, when one of three drugs is used first. The cost-effectiveness ratio for clobazam, lamotrigine and vigabatrin have been calculated. The expected cost per patient of treatment over the 1-year period was up to 50% higher with vigabatrin and lamotrigine compared with clobazam, with a cost-effectiveness ratio around 40% higher.
منابع مشابه
Cost-effectiveness model of adjunctive lamotrigine for the treatment of epilepsy.
OBJECTIVE To predict the cost-effectiveness of lamotrigine by evaluating the costs and health outcomes in treated patients. BACKGROUND Lamotrigine adjunctive therapy has been found to be associated with decreased seizure frequency and severity in patients who are refractory to treatment with the older antiepileptic drugs (AEDs). METHODS We used a cost-effectiveness clinical decision analysi...
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عنوان ژورنال:
- Seizure
دوره 4 شماره
صفحات -
تاریخ انتشار 1995